|
KMID : 0369819710010010030
|
|
Jorunal of Korean Pharmaceutical Sciences
1971 Volume.1 No. 1 p.30 ~ p.33
|
|
|
Study on the analgesic Effect of Salicylamide and Combined with some Parasymptholytics and Serveral Antihistaminics
|
|
김길향/Kim KH
김재완/우종학/김신근/KIm JW/Woo CH/Kim SK
|
|
|
Abstract
|
|
|
|
Comparative studies were made on the analgesic effect of salicylamide, used individually and combined with parasympatholytics (propantheline and atropine) and antihistaminics (tripelennamine, diphenhydramine) as regards the analgesic effect (in thermal contact method) were examined by its oral administration with each combined drug to mouse (three assumption cross-over test), and the following effects were found. 1. The increasing order of the parasympatholytics to the analgesic effect of salicylamide is as follows: propantheline>atropine. 2. The increasing order of the antihistaminics to the analgesic effect of salicylamide is as follows: chlorpheniramine>diphenhdramine>tri pelennamine. In the ratio '1 : 1' salicylamide to parasympatholytics and antihistaminics, the analgesic effect of salicylamide was more increase than the other ratio in this study.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|